Chronic Kidney Disease

Urinary & RenalAll SpeciesNew

Key Points

Chronic kidney disease (CKD) is a progressive, irreversible loss of functional nephrons and therefore renal function
While many conditions can cause CKD (infection, obstruction, neoplasia, toxins, etc.) the end result is fibrosis and loss of renal fun
Early clinical signs include polyuria, polydipsia, weight loss, inappetence and dehydration, progressing to vomiting, halitosis, oral ulceration and anaemia as renal function decreases
Diagnosis relies on identification of reduced renal function through bloodwork, urinalysis and imaging
- Blood pressure should always be checked in these patients as CKD causes systemic hypertension
Treatment focuses on slowing progression of disease through dietary management, blood pressure regulation and supportive care
Reducing the risk of renal injuries and getting regular vet checks are key to prevention

Differential Diagnoses

Renal lymphoma
Diabetes mellitus
Hyperthyroidism (cats)
Urinary obstruction

Educational content only. This factsheet is for general veterinary education and is not a substitute for professional veterinary advice, diagnosis, or treatment. Not for use in an emergency — contact a veterinarian or emergency service. Full disclaimer →